{"id":3331,"date":"2024-06-19T11:11:11","date_gmt":"2024-06-19T10:11:11","guid":{"rendered":"https:\/\/www.hausmanngalenica.com\/producto\/plantagen-forte\/"},"modified":"2026-01-28T09:55:36","modified_gmt":"2026-01-28T08:55:36","slug":"plantagen-forte","status":"publish","type":"product","link":"https:\/\/www.hausmanngalenica.com\/pt-pt\/producto\/plantagen-forte\/","title":{"rendered":"PLANTAGEN FORTE"},"content":{"rendered":"

Descri\u00e7\u00e3o<\/span><\/h4>\n

A sinergia dos diferentes componentes de Plantagen Forte, permitem obter um produto com uma alta biodisponibilidade do seu principal princ\u00edpio ativo, a curcumina.<\/p>\n

O componente principal de Plantagen Forte \u00e9 um extrato de rizoma de curcuma, altamente concentrado, purificado e obtido por cristaliza\u00e7\u00e3o. Este processo est\u00e1 patenteado e permite extrair os dois derivados principais da curcumina, a desmetoxicurcumina e a bisdesmetoxicurcumina. Desta forma obt\u00e9m-se um preparado altamente sol\u00favel e com maior biodisponibilidade via oral, o que aumenta a sua efic\u00e1cia.<\/p>\n

Curcumina em micelas polim\u00e9ricas que favorecem sua assimila\u00e7\u00e3o e atinge uma quantidade superior a outras c\u00farcumas do mercado com a quantidade utilizada.<\/p>\n

A curcumina presente no\u00a0Plantagen Forte<\/b>\u00a0foi submetida aos mais estritos controlos de forma independente pelos laborat\u00f3rios Phycher em Fran\u00e7a outorgando-lhe um grau de seguran\u00e7a e efic\u00e1cia dos mais elevados do mercado.<\/p>\n

Tem o certificado de qualidade ISO 22000.<\/p>\n

Advert\u00eancias<\/h4>\n

Hipersensibilidade a algum dos componentes<\/p>\n

Apresenta\u00e7\u00e3o<\/h4>\n

Caixa com 40 c\u00e1psulas de 616 mg<\/span><\/span><\/p>\n

Bibliografia<\/h4>\n

1.- Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med 1998; 64:1167-1172.<\/p>\n

2.- Surh YJ, Chun KS, Cha HH, y cols. Molecular mechanisms underlying chemo-preventive activities of anti- inflammatory phytochemicals: downregulation of COX-2 and iNOS through suppression of NF-?B activation. Mutation Research 2001; 480-481:243-268.<\/p>\n

3.- Dunsmore KE, Chen PG, Wong HR. Curcumin, a medicinal herbal compound capable of inducing the heat shock response. Crit Care Med 2001; 29:2199-2204.<\/p>\n

4.- Chang D-M. Curcumin: a heat shock response inducer and potential cytoprotector. Crit Care Med 2001; 29; 2231- 2232.<\/p>\n

5.- Jovanovic SV, Boone CW, Steenken S, Trinoga M, Kaskey RB. How curcumin preferentially works with water soluble antioxidants. J Am Chem Soc 2001; 123:3064-3068.<\/p>\n

6.- Gaedeke J, Noble NA, Border WA. Curcumin blocks multiple sites of the TGF-? signaling cascade in renal cells. Kidney International 2004; 66:112-120.<\/p>\n

7.- Srinisan P, Libbus B. Mining MEDLINE for implicit links between dietary substances and diseases. Bioinformatics 2004; 20:1290-1296.<\/p>\n

8.- Akhilender Naidu K, Thippeswamy NB. Inhibition of human low density lipoprotein oxidation by active principles from spices. Mol Cell Biochem 2002; 229:19-23.<\/p>\n

9.- Choudhuri T, Pal S, Pal S, Agwarwal ML, Das T, Sa G. Curcumin induces apoptosis in human breast cancer cells through p53-dependent Bax induction. FEBS Letters 2002; 512:334-340.<\/p>\n

10.- Shao Z-M, Shen Z-Z, Liu C-H, Sartippour MR, Go VL, Heber D, Nguyen M. Curcumin exerts multiple suppressive effects on human breast carcinoma cells. Int J Cancer 2002; 98:234-240.<\/p>\n

11.- Radhakrishna Pillai G, Srivastava AS, Hassanein TI, Chauhan DP, Carrier E. Induction of apoptosis in human lung cancer cells by curcumin. Cancer Letters 2004; 208:163-170.<\/p>\n

12.- Zheng M, Ekmekcioglu S, Walch ET, Tang CH, Grimm EA. Inhibition of nuclear factor\u2013 ?B and nitric oxide by curcumin induces G2\/M cell cycle arrest and apoptosis in human melanoma cells. Melanoma Res 2004; 14:165-171.<\/p>\n

13.- Han S-S, Keum Y-S, Seo H-J, Surh Y-J. Curcumin suppresses activation of NF-?B and AP-1 induced by phorbol ester in cultured human promyelocytic leukaemia cells. J Biochem Molecul Biol 2002; 35:337-242.<\/p>\n

14.- Bharti AC, Shishodia S, Reuben JM y cols. Nuclear factor- ?B and STAT3 are constitutively active in CD138+ cells derived from myeloma patients and suppression of these transcription factors leads to apoptosis. Blood 2004; 103:3175-3184.<\/p>\n

15.- Liontas A, Yeger H. Curcumin and resveratrol induce apoptosis and nuclear translocation and activation of p53 in human neuroblastoma. Anticancer Res 2004; 24:987-998.<\/p>\n

16.- Elattar TMA, Virji AS. The inhibitory effect of curcumin. Genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro. Anticancer Res 2000; 20:1733-1738.<\/p>\n

17.- Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P, Aggarwal BB. Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines. Oncogene 2001; 20:7597-7609.<\/p>\n

18.- Nakamura K, Yasunaga Y, Segawa T y cols. Curcumin down-regulates AR gene expression in prostate cancer cell lines. Int J Oncol 2002; 21:825-830.<\/p>\n

19.- Hour TC, Chen J, Huang CY, Guan JY, Lu SH, Pu YS. Curcumin enhances cytotoxicity of chemotherapeutic agents in prostate cancer cells by inducing p21WAFI\/CIPI and C\/EBP? expressions and suppressing NF-?B activation. The Prostate 2002; 51:211-218.<\/p>\n

20.- Deab D, Jiang H, Gao X y cols. Curcumin sensitizes prostate cancer cells to tumor necrosis factor-related apoptosis-inducing ligand\/Apo2L by inhibiting nuclear factor- ?B through suppression of I?B? phosphorylation. Mol Cancer Ther 2004; 3:803-812.<\/p>\n

21.- Cheng AL, Hsu CH, Lin JK y cols. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res 2001; 21:2895-2900.<\/p>\n

22.-Mahady GB, Pendland SL, Yun G, Lu ZZ. Turmeric (Curcuma longa<\/i>) and curcumin inhibit the growth of Helicobacter pylori, a group 1 carcinogen. Anticancer Research 2002; 22:4179-4182.<\/p>\n

23.- Foryst-Ludwig A, Neumann M, Schneider-Brachert W, Naumann M. Curcumin blocks NF-?B and the mitogenic res ponse in Helicobacter pylori-infected epithelial cells. Biochem Biophys Res Com 2004; 316:1065-1072.<\/p>\n","protected":false},"excerpt":{"rendered":"

Suplemento alimentar \u00e0 base de raiz de c\u00farcuma concentrada e padronizadaComplemento alimenticio a base de ra\u00edz de c\u00farcuma concentrada y estandarizada.<\/p>\n","protected":false},"featured_media":7295,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false},"product_brand":[],"product_cat":[72],"product_tag":[159],"class_list":{"0":"post-3331","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-botania-pt","7":"product_tag-ossos-e-articulacoes","9":"first","10":"instock","11":"purchasable","12":"product-type-simple"},"acf":[],"yoast_head":"\nPLANTAGEN FORTE • Hausmann Gal\u00e9nica<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.hausmanngalenica.com\/pt-pt\/producto\/plantagen-forte\/\" \/>\n<meta property=\"og:locale\" content=\"pt_PT\" \/>\n<meta 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